Chemotherapy Drugs: Little known side effect YOU need to know about! (2)

by: James Arond-Thomas, MD

At the Center for Learning about Healing in Ann Arbor, MI where I practice integrative medicine and behavioral oncology, I focus on multi-dimensional ways to empower patients to evaluate and change patterns of eating, behaving, thinking, and coping that are known to contribute to inflammatory reactions in the body. These methods complement the cancer killing effects of Paclitaxel, Doxorubicin, 5-FU, and other such drugs.

Genomic Testing Can Clarify Your Specific Inflammatory Molecular Mechanisms that Sustain Your Cancer

Inflammation is present before, and during the life of a cancer. In cancer, inflammation is a pathological process characterized by injury or destruction of tissues caused by a variety of cellular and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. However, inflammation is also essential for tissue repair and tissue rebuilding. Genomic testing (easily performed with saliva or blood samples) allows us to create a personalized map of your inflammatory tendencies based on your genomic predispositions. This method is revolutionary because it allows you to regulate your genomic capabilities to your advantage, which then allows you to reduce the expression of your inflammation-related genes.

What Cancer Patients Need to DO is
Reduce the Expression of Inflammation-Related Genes

Once you know your specific genomic blueprint for excessive inflammation, we work together to develop the tools you need to re-set the expression of your inflammation blueprint. These tools must be unique to you, precisely because your genomic expression capabilities are unique to you. These tools include anti-inflammatory diets supported by oral and intravenous nutrients that block and down-regulate NF-kB. Remember, it is this protein that is responsible for the abnormal rise in IL-8 during Paclitaxel administration. By measuring markers of cellular inflammation before, during, and after chemotherapy treatment, and using your unique tools, we compile a personalized treatment record of inflammatory responses (normal and abnormal) that serves as a benchmark for your risk of cancer recurrence after chemotherapy treatment.

With these personalized guidelines, you will have insider knowledge about choices of foods, behaviors, and interpersonal relationships that will be conducive to keeping your inflammation-related genes quiet. Patients with high inflammatory markers during chemotherapy are at higher risk for recurrence, and thus need to more closely monitor and modulate their NF-kB expression after the chemotherapy ends.

What is important to understand is that:
- There is an optimal amount of expression of NF-kB consistent with health;
- Excessive expression contributes to diseases like cancer recurrence, especially when NF-kB is turned on continuously; and
- You will have the power and the tools needed to regulate NF-kB’s expression.

Become the Captain of Your Healing Team!

As your physician-coach, I recommend that you become the captain of your healing team, and let me and my team partner with you to clarify the specific molecular mechanisms driving your specific cancer. We coach you to learn the skills and to master the tools needed to reduce the collective contribution of foods, emotions, and behaviors to the excessive expression of inflammation-related genes. By working together, you learn to modulate your inflammation blueprint by modulating the expressive capacity of NF-kB. Modulating your expression of NF-kB is the inner game of self-discovery, consciousness expansion, forgiveness, and cell (self) renewal that is what allows healing to occur. (To view diagrams describing NF-kB in health and in disease, visit our website at http://www.arond-thomasonline.com!)

Learn More about How You Can Improve Your Chances of Not Having a Cancer Recurrence…

You or a loved one can learn more about how you can improve the effectiveness of your cancer treatments and improve your chances of not having a recurrence. at http://www.1CancerCoach.com.

Chemotherapy Drugs: Little known side effect YOU need to know about!

by: James Arond-Thomas, MD

In January, 2005 it was reported that cancer has surpassed heart disease – for the first time – as the top killer of Americans younger than 85. In 2002, the most recent year for which information is available, 476,009 Americans younger than 85 died of cancer, compared with 450,637 who died of heart disease. An estimated 1,372,910 new cancer cases and 570,260 cancer deaths are expected this year.

Paclitaxel, a preferred treatment for lung and breast cancers, has a cancer-promoting risk as well….

Lung cancer remains the biggest cancer killer, projected to claim 163,510 lives this year. Paclitaxel will be used in the attempt to save the lives of many of these patients. However, one little-known effect of Paclitaxel is that in a subset of these patients there will be up to a fivefold increase in the production of Interleukin – 8 (IL-8) – a cellular communication molecule that initiates the growth of new blood vessels to feed the growing cancer. In other words, if you fall into this subset of patients, treatment using Paclitaxel alone may not be effective at preventing recurrence.

NF-kB blockade enhances cancer killing ability of Paclitaxel!

IL-8 is under the control of an inflammatory regulating protein called nuclear factor-kappa Beta (NF-kB). When the activation of NF-kB is blocked, IL-8 dries up, much like a faucet that has been turned off. Thus, blocking NF-kB activation enhances the cancer killing ability of Paclitaxel. These results were seen with many types of cancer cells, including lung and esophageal cancer cells.

Paclitaxel is NOT the Only Drug that Promotes Excessive NF-kB

Paclitaxel is but one of a group of drugs that has this unwanted side-effect of activating NF-kB. Other drugs in this group include Doxorubicin, 5-Fluorouracil, Cisplatin, VP-16 (Etoposide), ARA-C, and Methotrexate. In addition, research demonstrates that excessive NF-kB activity contributes to cancer development in the following types of cancers: non-small cell lung cancer, pancreatic, primary liver, head and neck cancer, prostate, breast, esophageal, stomach, colon, Hodgkin’s disease, and multiple myeloma.

Supportive treatment that improves chemotherapy effectiveness…..

Paclitaxel, along with the other NF-kB activating chemotherapeutic drugs, is approved for the treatment of a wide range of cancers. It appears likely that they will continue to be used for the foreseeable future. If you are on (or considering using) Paclitaxel or one of the other drugs in this group to treat cancer, there is a supportive treatment that you need to know about that improves the effectiveness of these drugs and reduces your risk of having a cancer recurrence.

We have a Multi-Dimensional Approach to Reducing Inflammation that Complements and Enhances the Impact of these Drugs!

Breast cancer for beginners

by: Mansi gupta

Introduction
Because of the social changes, which has brought increased number of workingwoman and hence delayed childbearing, there has been a steep rise in the number of breast cancer patients in the last few decades. But as the incidence of the patients has risen so has raised the modality of treatments and the success rates. Also scientists have devised methods by which the cancer can be detected in an early stage and it has been convincingly proved that early detection and treatment bears a better prognosis than the later stage.

Myths
There are many myths attached to breast cancer. Some think that any lump in breast is a breast cancer but to the contrary most of them are benign. Similarly it was a popular belief earlier that breast-feeding decreases one’s risk of the cancer but that has been now found to be untrue. Some say that mammography makes the breast cancer widespread but it’s not true. Similarly there are many other myths, which need to be cleared in mind of the general mass for the proper detection and management of the tumor.

Early detection
Breast cancer can be detected in an early stage if women are taught to self-examine their breast. In case of detection of any breast lump or of any slightest suspicion, mammography should be done to rule out any tumor. Mammography is a good tool to diagnose this type of cancer.

Statistics
The incidence of breast cancer is increasing at an alarming rate. It is said that every 2-3 minutes one American woman is diagnosed a breast cancer.

Cause
Although the cause is not fully understood but it is hypothesized that there are various factors such as genetic and environmental. The environmental factors are increased age, obesity, smoking and having the first child at late age.

Diagnosis
The findings that denote a cancer are single, non-tender and firm to hard mass with ill-defined margins. This can be later confirmed by mammography and biopsy. After the cancer has been diagnosed staging is done to find out the best treatment option as well as the prognosis.

Management
The management of breast cancer rests basically on two things. The first is the treatment and second is the counseling. The treatment can further be divided into three: medical, radiation, and surgery. The medical treatment consists of drugs such as tamoxifen, which is an anti estrogen, aromatase inhibitors such as aminoglutethimide and monoclonal antibodies such as trastuzumab. But similar to other drugs they have their own side effects profile. The side effects associated with tamoxifen are increased vaginal bleeding, endometrial cancer and cataracts. The aromatase inhibitors have the side effects of leg cramps, jaundice and weight gain while the monoclonal antibodies may cause sterility or certain birth abnormalities.
Generally the radiation and surgery are the modalities, which are needed for the treatment to ward off the body of the cancerous growth.

Counseling
This is one of the most important parts of the treatment both before and after the surgery. The patients are to be taught that this is only another disease, which has treatment available, and persons can lead a normal life after that.

Latest research
Latest research is being done on both the surgery and the medicine. For the surgery, surgeons are trying to find out the best way of surgery so that post surgery the patients have minimal disabilities. Similar medicines with lesser side effects are being researched.

Lighting the Way to Fight Breast Cancer

by: ARA

Being a woman and getting older are the main risk factors for breast cancer. This year, more than 200,000 women in the United States will be diagnosed with breast cancer, and nearly 40,000 women will lose their lives to the disease. Although you cannot control your sex or age, there are other factors related to personal, everyday choices that can be controlled, and may help reduce your risk for breast cancer.

Control Your Risk Factors

The risk factors you can control that may decrease your risk of getting breast cancer include: not having more than one drink of alcohol per day; not being overweight after menopause nor gaining weight as an adult; not taking birth control pills for five years or longer; and having children, especially before the age of 30.

Eat Right and Exercise

For overall wellness and also to possibly decrease the risk for developing breast cancer, it is recommended that women consume a well-balanced diet rich in fruits and vegetables. Physical activity may protect you from breast cancer if you are pre-menopausal or are a younger postmenopausal woman. Exercise reduces estrogen levels, fights obesity, lowers insulin levels and boosts the immune system.

Support the Fight Against Breast Cancer Where You See the Pink Ribbon

Another important piece you can control is your support of organizations that are leading the fight against breast cancer, often with the help of retail partners. For seven years, Pier 1 Imports has sold the “Komen Candle” with 25 percent of the purchase price (less tax) benefiting the Susan G. Komen Breast Cancer Foundation to support innovative breast cancer research and community outreach programs. Last year, sales of the candle raised more than $176,000 for the Komen Foundation.

“A key to our success at the Komen Foundation is that we collaborate with a variety of companies and organizations to provide creative ways for people to make a difference in the fight against breast cancer,” said Cindy Schneible, vice president of cause-related marketing and sponsorship for the Komen Foundation. “ Pier 1’s ‘Komen Candle’ enables the Komen Foundation to reach more women with the life-saving message of early detection and to raise funds for breast cancer research, education, screening and treatment programs.”

Starting late August, the signature Floral Blush-scented candle will be sold in Pier 1 stores nationwide. For more information about breast health or breast cancer, call the Komen Foundation’s National Toll-Free Breast Care Helpline at (800) I’M AWARE (462-9273) or visit the Web site at www.komen.org.

ALL ABOUT CURADERM BEC5!

by: Moana Korikalo

Where you can Find Curaderm BEC5;
1. stopskincancer.com
2. skincanceradvice.info
3. cureskincancertoday.com
4. nomoreskincancer.info
and 5. skincancerdoctor.info

The Uses of Curaderm BEC 5

Curaderm is a medicine used to treat areas of the skin which may have been discolored, thickened or scaly as a result of exposure to sun (UV) light. Skin cancers such as keratoses. basal cell carcinoma, and squamous cell carcinoma and Non-melanoma’s.

Do you know What Curaderm BEC5 is?
Curaderm is a cream extracted from a plant called the Devils Apple Fruit.
The active ingredient in Curaderm is Solasodine Glycosides (BEC.)
These active ingredients are extracted from the plant Solanum sodomaeum.
The active has been shown to be effective in the treatment of the malignant human
skin tumors.

What Does Curaderm BEC5 Contain?
Curaderm BEC 5 consists of active anticancer ingredient Solasodine Glycosides. Therefore it’s commonly known as BEC5. It also contains Saliyclic Acid and Urea at a very high concentration. This assists the BEC 5 to kill cancer cells. (Note: Saliyclic Acid and Urea may irate the skin.)

Curaderm is Non toxic, Non mutagenic, does not affect the heartbeat or blood flow.
And is a Biochemical, haematological and Uri analytical studies demonstrated that
there were no adverse effects on the liver, kidneys or haematopoietic system (blood cells) during and after treatment.

The Expectations of Curaderm BEC5.

The normal reactions seen when applying daily (at least twice) the curaderm BEC5 to the lesion or affected areas are some degree of redness and swelling, tingling sensation or pain which can be experienced for 30-60minutes.

The pattern of responses can be anticipated by: reddening, then usually erosion, ulceration and decline of the treated of the unwanted cells followed by the re-growth of the normal skin tissue.
(Note: During treatment of the lesions may appear worse than before treatment. That is because BEC seeks and destroys the cancer cells that are non-visible to the naked eye)

The Recommendations of Curaderm BEC5.

When using Curaderm BEC5 there is no scar formation of skin tissue. You will not lose the re-growth of normal tissue.

There is limited access to the cancer if it exists within the lesion if it is deep within the skin. And there is a low rate of the reoccurrence of the skin cancer.

Attack of the Cancer Fighting Tomatoes (2)

by: Michael Brooks

Gann et al. 1999 - Cancer Research
The study examined initial plasma caroteniods (including lycopene) of 1872 men in 1982, and then followed them for 13 years. These men were randomly assigned to a placebo group or a group to receive beta-carotene and aspirin supplementation. Of the men studied, 578 developed prostate cancer versus 1294 control subjects. Lycopene was the only antioxidant with a significantly lower average blood level in those men with cancer as compared to those without cancer. In those men not receiving the aspirin and beta carotene, plasma lycopene levels were very strongly related to a lower risk of developing prostate cancer. This study concluded that increased consumption of tomato products and other lycopene-containing foods may reduce the onset of prostate cancer.

Giovannucci 1999 - Journal of the National Cancer Institute
This journal is a review of research studies available regarding cancer risk (not just prostate cancer) and intake of tomato based foods as well as blood lycopene levels. After identifying 72 studies that fit these criteria, it was found that an inverse relationship between tomato intake or blood lycopene levels and cancer risk was reported in 57 of them. Of these 57, it was found that 35 of these inverse relationships were statistically significant. It was also found that cancer protection from lycopene was strongest for prostate, colon and stomach cancers, but also appeared to have some benefit in the treatment of other cancers.

Rao et al. 1999 - Nutrition and Cancer
This study examined plasma and prostate lycopene levels in cancer patients and a control group free of cancer. Though only 12 patients were in each group, significantly lower serum and prostate lycopene levels were found in those with cancer. Levels of other carotenoid substances did not vary between the groups.

Additional Benefits

In addition to fighting cancer, the lycopene found in tomatoes has been associated with better mental activity in old age and a reduced risk of heart disease. A University of Maryland study found that tomatoes might protect the eyes by hampering macular degeneration, a cause of vision loss in older adults.

How do I get Lycopene into my body?

The best source of lycopene intake is through eating tomato-based products. This is more effective than supplementation. You will get the most lycopene through concentrates and processed products such as tomato paste, sauce, soup and canned tomatoes. Heating helps to release lycopene and adding a little light olive oil will increase absorption. Start packing your diet with more tomato based recipes and begin enjoying the cancer fighting power of the mighty tomato.

Attack of the Cancer Fighting Tomatoes

by: Michael Brooks

That’s right, the colorful little fruit (yes, it’s a fruit) has been shown to pack a powerful punch against several forms of cancer. A variety of studies indicate that a diet rich in tomato based products (tomato paste, sauce, juice, soup and ketchup) can significantly reduce the risk of prostate, lung and colon cancer. Not bad for a fruit that was considered by many to be poisonous and inedible until the 19th century.

What is the Active Ingredient?

The active ingredient that makes tomatoes such a formidable opponent against cancer cells is the carotenoid called Lycopene. Lycopene is the natural red pigment found in tomatoes and tomato based products. The redder the tomato, the more lycopene is present.

How does Lycopene Fight Cancer?

In the body, lycopene is deposited in the liver, lungs, prostate gland, colon and skin. Its concentration in body tissues tends to be higher than all other carotenoids. Some organs, such as the testes and adrenal glands, store higher levels of lycopene than do other organs or tissues. Lycopene acts as a super antioxidant by picking up free radicals in the body. Free radicals are atoms or groups of atoms with an odd number of electrons and can be formed when oxygen interacts with certain molecules. Once formed these highly reactive radicals can start a chain reaction. Their primary danger comes from the damage they can do when they react with important cellular components such as DNA, or the cell membrane. Cells may function poorly or die if this occurs.

Is there any Research on the Cancer fighting power of Lycopene?

Although more large-scale studies are needed before any definitive conclusions can be made, current research does suggest that lycopene from various tomato products is indeed associated with the lowered risk of several types of cancers. Several published reports are listed below.